Source: Clujul Medical. Jun, Vol.
Abstract: Neoadjuvant image-guided therapies comprises all locoregional treatment administred to hepatocellular caricinoma patients in order to maintain eligibility during liver transplantation waiting time: transcatheter arterial chemoembolization TACEselective internal radiation therapy SIRTchemical alcohol hepatic cancer imaging CAIradio frequency ablation RFA. This study was effectuated on a total of 56 patients with liver cirrhosis and HCC, which are waiting on the transplant list.
According to imaging appearance, compared with imaging study before treatment, the results were interpreted as such: tumor regression, identical size and tumor progression.
The treated HCC nodules were analyzed by pathology at the time of liver transplantation.
- Ultrasound abdominal transparietal and intraoperativemultidetector computed tomography CT and MRI are the methods of choice to achieve these objectives.
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- Journal of Gastrointestinal and Liver Diseases
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The follow up was made clinically, biologically alpha-fetoprotein AFP level, and imaging at one month after treatment and every 3 months after transplantation. The average time between hepatic cancer imaging up the transplantation was Residual tumor or tumor progression hepatic cancer imaging index nodule level was proven in 14 patients; 8 patients had new lesions.
In high-risk patients, HCC screening protocols can lead to an earlier detection and at a treatable stage of the disease. Keywords Multiparametric Magnetic Resonance Imaging, diagnosis, hepatic cancer imaging carcinoma Rezumat Carcinomul hepatocelular CHC este cea mai frecventă tumoră malignă primară a ficatului, asociată hepatic cancer imaging cu ciroza, cu o incidenţă crescândă la nivel mondial. Protocoalele de screening al CHC la pacienţii cu risc crescut pot duce la detectarea mai precoce şi într-un stadiu tratabil al bolii. Patients with haemochromatosis are at increased risk for HCC; obesity and diabetes associated with non-alcoholic steatohepatitis are other factors that may be associated hepatic cancer imaging HCC 1. Imaging, in particular Multiparametric Magnetic Resonance Imaging MP MRI represents a key element in the diagnostic algorithm and in the multidisciplinary customized management of each patient, allowing the number and size of tumoral nodules, their semiology, the involvement of intra- and extrahepatic vascular structures portal venous structures — PV, hepatic veins — HV, inferior vena cava — IVCthe presence extrahepatic spread, the existence of anatomical variants or other incidentally discovered lesions
On pretransplant imaging followup 38 of 68 nodules were stable or in regression. Contrast imaging exams hepatic cancer imaging a tendency of underestimating viable tumor fraction of the treated lesions and can omit new tumor sites.
Neoadjuvant therapy are palliative unable to provide a cure for HCC. They are useful by improving outcomes and represents a bridge to liver transplantation.
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