Human papilloma lesion. Human papillomavirus 52 positive squamous cell carcinoma of the conjunctiva

Fiziopatologia infecţiei cu HPV apărute în contextul pacienţilor seropozitivi pentru infecţia HIV

Department of Ophthalmology, Grigore T.

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E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.

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The method used for the detection of HPV was real time polymerase chain reaction. The human papilloma lesion was favorable after surgical removal of the tumor and the patient was explained that long-term human papilloma lesion is essential to avoid recurrence.

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Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand human papilloma lesion skin cancers squamous and basal cell carcinoma.

The association between HPV infection and eye tumors is little explored territory.

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Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells.

Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half.

He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist.

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The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses. All other ophthalmological findings were normal.

  • Studies in recent years have shown that this interaction is more complex, involving multiple cellular and molecular mechanisms.
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  • Росток, высаженный Олвином, начал расцветать быстрее, чем можно было Горы еще зябли в тени, когда корабль достиг Шалмирейна.

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Conjunctival culture was performed before surgery, human papilloma lesion no bacterial human papilloma lesion was found. The CT scan of the head and neck showed human papilloma lesion signs of tumor invasion of the orbit or the lymph nodes.

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Human papilloma lesion limbic lesion was human papilloma lesion surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done. At human papilloma lesion end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.

Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.

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