Study of Targeted Therapy for HER2-Positive Metastatic Breast Cancer
Recent research offers previously unavailable opportunities to make substantial progress in GC therapy. Targeted therapies have revolutionized GC treatment, but benefit remain limited, with only a few months increase in overall survival.
The current challenge is the proper stratification of patients, in order to implement an adequate therapy, and to identify primary and acquired resistance to treatment. As such, this project focuses on the valorification of the research infrastructure of the partners.
Results could have a major importance in the field of gastric cancer therapies, contributing to an improved quality of life and overall survival gastric cancer targeted therapy Gastric cancer targeted therapy patients, by translating scientific results in new opportunities of personalized treatment. Main objective THERRES is an extremely ambitious and innovative project, focusing on the association of immunotherapy with molecular oriented drugs in gastric cancer, as a modern method of treatment.
Gastric cancer targeted therapy project aims to implement a new classification system to distinguish between gastric cancer subtypes and to characterize regulatory molecules of immune function immune checkpoints Specific objectives: Objective 1: Identification of biomarkers gastric cancer targeted therapy potential therapy targets in GC subtypes defined on the basis of recent genomic classifications Objective 2: Identifying response and resistance biomarkers to standard anti-HER2, anti-MET and anti-VEGF therapy in GC Objective 3: Characterizing vascular stroma particularities in GC, including the role on immune checkpoints in GC subtypes.
As a key result, the project gastric cancer targeted therapy generate instruments to guide treatment decisions and help in the management of GC patients through a personalized approach.
The result of the present project will contribute to improving the performance, quality and international visibility of Romanian scientific results in the oncology field. Institutul nostru are analiza helminti chisinau veche traditie in patologia dificila cardio-vasculara, hepatica, renala, digestiva, hematologica, etc.
La inceput de mileniu III specialistii din Institutul Clinic Fundeni sunt pregatiti sa abordeze asemenea probleme nu numai prin prisma practicii de zi cu zi, ci si sub aspectul cercetarii fundamentale.